PHEN is a noradrenergic drug, which is theorized to affect food intake primarily via the enhancement of norepinephrine release and possibly via the blockade of norepinephrine reuptake as well. It has been available in the US since 1959 for short-term (generally regarded as 12 weeks) treatment of obesity in dose range of 15 mg/day to 37.5 mg/day.Mar 9, 2020 · However, the EMA has not approved this medication due to its abuse potential, the lack of long-term data on the cardiovascular effects of phentermine, and the cognitive side effects of topiramate—attention, language, and memory impairment . As this drug combination contains phentermine, it is a controlled DEA schedule IV substance. The table below lists prescription drugs approved by the FDA for weight loss. The FDA has approved five of these drugs—orlistat (Xenical, Alli), phentermine-topiramate (Qsymia), naltrexone-bupropion (Contrave), liraglutide (Saxenda), and semaglutide (Wegovy)—for long-term use.Aug 3, 2023 · What Is Wegovy? Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obesity) or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e ... Aug 22, 2021 · Indeed, in the wake of the fen-phen problems, the FDA rejected all drug company efforts to win approval for new weight-loss drugs between 1999 and 2012. Since then, it has approved four drugs for ... Summary. Commonly reported side effects of orlistat include: bowel urgency, frequent bowel movements, oily evacuation, oily rectal leakage, steatorrhea, and flatulence with discharge. Other side effects include: fecal incontinence. Continue reading for a comprehensive list of adverse effects. Applies to orlistat: oral capsules.Uses. This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who ...May 15, 2023 · On the positive side, lower doses of semaglutide, the active ingredient in Wegovy, have been used to treat diabetes for several years now, though UpToDate, a site that aggregates research about treatments to support decision-making by physicians, notes that there have been very few trials lasting more than four years, so the long-term safety of ... Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use.The most common side effects are tingling in the hands and feet, dizziness, change in taste, trouble sleeping, constipation and dry mouth. Qsymia can also increase your resting heart rate, affect ...Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ...diarrhea. dry mouth and tongue. bad taste in your mouth. constipation*. headaches*. mild allergic reaction *†. * To learn more about this side effect, see the “Side effects explained ...diarrhea. dry mouth and tongue. bad taste in your mouth. constipation*. headaches*. mild allergic reaction *†. * To learn more about this side effect, see the “Side effects explained ...Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain.7. Wegovy (semaglutide) Wegovy is the newest FDA-approved weight-loss medication and works much the same way as Saxenda, by mimicking the action of the hormone GLP-1 to suppress hunger. Wegovy is a once-a-week injectable. Dosage is increased over the course of several weeks-to-months, until a 2.4 mg dose is achieved.May 3, 2023 · 1. Nausea and vomiting. Nausea is the most common semaglutide side effect. Up to 20% of people taking it for Type 2 diabetes reported nausea in clinical trials. Nausea is even more common if you’re taking the higher-dose version for weight loss. Vomiting tends to be less common than nausea. weight loss. impaired taste (changes in how things taste) trouble with memory. More common side effects in people taking Topamax for epilepsy include: tingling in the legs and arms. loss of ...Jan 1, 2014 · Phentermine has the advantage of low cost and many years of clinical experience, but its long-term use is considered off-label, long-term effects on CVD outcomes are unknown, and most use has been a few months or less. 41 There are even fewer data for long-term safety and efficacy of the other noradrenergic agents. Orlistat has a reasonably ... 1. Nausea and vomiting. Nausea is the most common semaglutide side effect. Up to 20% of people taking it for Type 2 diabetes reported nausea in clinical trials. Nausea is even more common if you’re taking the higher-dose version for weight loss. Vomiting tends to be less common than nausea.May 19, 2016 · Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances. 7. Wegovy (semaglutide) Wegovy is the newest FDA-approved weight-loss medication and works much the same way as Saxenda, by mimicking the action of the hormone GLP-1 to suppress hunger. Wegovy is a once-a-week injectable. Dosage is increased over the course of several weeks-to-months, until a 2.4 mg dose is achieved.May 19, 2016 · Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances. Side effects Interactions FAQ What is Qsymia? Qsymia contains a combination of phentermine and topiramate in an extended-release capsule. Phentermine is an appetite suppressant similar to an amphetamine. Topiramate is typically used as a seizure medication, also called an anticonvulsant.On July 17, 2012, the FDA approved a tablet combining phentermine plus extended-release topiramate (Qsymia, Vivus) for weight loss. Phentermine has been used for weight loss, and topiramate is an antiepileptic agent that has been commonly associated with weight loss as a side effect. The doses approved for weight reduction are lower than either ...Phentermine is an effective weight loss pill, but due to stimulating effects, it may induce withdrawal symptoms in some people. Withdrawal symptoms occur when the brain is trying to adjust to the new situation. Persons experience symptoms such as fatigue, irritability, bad mood, among others.Diphenhydramine is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes /nose/throat, cough, runny ...Phentermine and Qsymia are both medications used for weight loss. Phentermine is only approved for short-term usage, while Qsymia is approved for long-term use. Topiramate is a medication used to treat seizures and prevent migraines. It also happens to have a noticeable weight loss effect, although it’s not approved in Canada solely for ...I have been on Qsymia since 2016, I lost 45 lbs and have kept it off since then. I weigh 163 and wish I could lose at least 8 more lbs, but I have plateaued. I have been taking it this long and had no side effects only at the first 2 weeks I had the tingling sensation on my legs.Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances.Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain.Common Side Effects of Weight Loss Drugs. Increased blood pressure and heart rate, insomnia, nervousness, restlessness, dependence, abuse or withdrawal may occur with long-term use. When given as a single agent, phentermine is not implicated in valvular heart disease; avoid use at bedtime. Jan 28, 2023 · Saxenda Side Effects: Long-term use of Saxenda can lead to dangerous effects, such as suicidal thoughts, impaired kidney function, pancreatitis, gallbladder disease, and increased heart rate. Short-Term Diet Pills Side Effects: Due to amphetamine-type effects, medications approved for short-term use can cause elevated heart rate and blood ... On July 17, 2012, the FDA approved a tablet combining phentermine plus extended-release topiramate (Qsymia, Vivus) for weight loss. Phentermine has been used for weight loss, and topiramate is an antiepileptic agent that has been commonly associated with weight loss as a side effect. The doses approved for weight reduction are lower than either ...Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances.Common side effects of phentermine and topiramate may include: joint pain, ankle sprain; flu -like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems ( insomnia ); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, thoughts about ...Qsymia Dosage and Administration. Take orally once daily in morning. Avoid administration in evening to prevent insomnia ( 2.3 ). Recommended starting dosage is 3.75 mg/23 mg (phentermine mg/topiramate mg) daily for 14 days; then increase to 7.5 mg/46 mg daily ( 2.3 ). Jul 18, 2021 · Paresthesia (tingling, numbness) of the extremities (15-38%) Dizziness (11-28%) Dysgeusia (abnormal taste sensation) (6-19%) Insomnia (7-17%) Constipation (6-16%) Dry mouth (5-14%) Headache (5-14%) Nausea (5-13%) Diarrhea (4-11%) Upper respiratory tract infection (4-9%) The latest weight loss drugs work in a new way to help you shed pounds with minimal side effects. Learn how they do it and why you take them long term. ... (Qsymia®): This medication also ...These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about ...Extreme happiness or sadness. Symptoms of dangerously high blood pressure, such as severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, or seizures. These symptoms can indicate a serious phentermine side effect.Jun 28, 2023 · Extreme happiness or sadness. Symptoms of dangerously high blood pressure, such as severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, or seizures. These symptoms can indicate a serious phentermine side effect. Jan 16, 2023 · Qsymia is significantly more expensive than phentermine-only pills, costing about $200 per month without insurance. The combined pill has a long list of potential side effects, including severe birth defects if taken while pregnant. This is a newer medication (FDA approval in 2012), so long-term side effects remain relatively unknown. Jan 11, 2023 · In general, Phentermine chemicals do have side effects on long-term treatment. One of the most common side effects is dry mouth. Aside from this, you may also experience nervousness or jitteriness ... weight loss. impaired taste (changes in how things taste) trouble with memory. More common side effects in people taking Topamax for epilepsy include: tingling in the legs and arms. loss of ...This combination consists of fixed lower doses of phentermine and topiramate (3.75/23, 7/46, 11.25/69 and 15/92 mg) and is available in capsules under the brand name Qsymia. Common side effects of phentermine include nervousness, excitability, insomnia, headache, dry mouth, sweating, tachycardia, palpitations, nausea, constipation, and thirst.Apr 26, 2023 · The combination of phentermine and extended-release topiramate (Qsymia) was approved by the FDA in July 2012 as an adjunct to a reduced-calorie diet and exercise for long-term weight management in individuals with an initial BMI of 30 kg/m 2 or higher (obese) or 27 kg/m 2 or higher (overweight) with at least one weight-related comorbid ... The FDA lists its typical side effects as possibly including nausea, dry mouth, diarrhea, GERD, and dry eye. 1 REPLY Updated December 26, 2021. Qsymia side effects after break. I was on Qsymia for about 16 months with no side effects. I lost 40 pounds at that time.trouble sleeping (insomnia) new or worse irritability acting aggressive, being angry, or violent acting on dangerous impulses an extreme increase in activity and talking (mania) other unusual changes in behavior or mood Serious eye problems which include: Aug 22, 2021 · Indeed, in the wake of the fen-phen problems, the FDA rejected all drug company efforts to win approval for new weight-loss drugs between 1999 and 2012. Since then, it has approved four drugs for ... Phentermine is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Phentermine belongs to the group of medicines known as appetite suppressants. This medicine is available only with your doctor's prescription.Common side effects of phentermine and topiramate may include: joint pain, ankle sprain; flu -like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems ( insomnia ); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, thoughts about ...Serious side effects vary by drug but can include depression, heart palpitations, fast or irregular heartbeat, increased blood pressure, dizziness, tremors, chest pain, and difficulty breathing ...Common side effects of Qsymia include: constipation, insomnia, nasopharyngitis, paresthesia, mood disorder, sleep disorder, and xerostomia. Other side effects include: urinary tract infection, anxiety, blurred vision, depression, dizziness, fatigue, influenza, nausea, increased serum creatinine, and dysgeusia.Symptoms of severe phentermine side effects include ( 3 , 4 ): Chest pain. Pounding or irregular heartbeat, or fluttering in your chest. Lightheadedness or faintness. Shortness of breath, even with only mild exertion. Swelling in your legs, ankles, or feet (edema) Slurred speech or weakness on one side of your body.Apr 21, 2022 · Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain. In clinical studies, patients lost the most weight after taking Contrave for 36 weeks and maintained weight loss through 56 weeks. In terms of phentermine weight loss, studies were only done for a short period of time. Once you stop phentermine, your appetite will return to normal. As a result, weight gain may occur.7. Wegovy (semaglutide) Wegovy is the newest FDA-approved weight-loss medication and works much the same way as Saxenda, by mimicking the action of the hormone GLP-1 to suppress hunger. Wegovy is a once-a-week injectable. Dosage is increased over the course of several weeks-to-months, until a 2.4 mg dose is achieved.ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ ᅠ Select Download Format Qsymia Long Term Side Effects Download Qsymia Long Term Side Effects PDF Download Qsymia Long Term Side Effects DOC ᅠ Bottle tightly closed when topiramate can think and pregnancy, food cravings to ensure that the sponsor. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about ...Qsymia is prescription-only weight loss medication that contains a combination of phentermine HCl and topiramate extended-release. This drug, which received FDA approval in 2012, helps manage obesity longer-term than phentermine alone, but also carries the risk of additional side effects (1, 2).diarrhea. dry mouth and tongue. bad taste in your mouth. constipation*. headaches*. mild allergic reaction *†. * To learn more about this side effect, see the “Side effects explained ...Phentermine-Topiramate Capsule, Extended Release Multiphase 24 Hr (Capsule, ER Hr) - Uses, Side Effects, and More Common Brand(S): Qsymia Generic Name(S): phentermine-topiramate In fact, this sort of weight loss is referred to as yo-yo dieting (yes, even if it comes secondary to the use of prescription medication) and can cause some serious long-term problems. #2. Using Phentermine Daily Can and Dose Cause Metabolic Damage. Perhaps the single biggest reason to avoid using Phentermine is that it can cause something ...Nov 2, 2022 · Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use. Tardive dyskinesia is a movement disorder that is a side effect of medications, especially first-generation antipsychotics. Less common causes are second-generation antipsychotics, antidepressants, mood stabilizers, antiepileptic drugs, movement disorder medications, antiemetics, and decongestants. Two medications have been approved to treat ...The Bottom Line. Qsymia is a prescription-only weight loss medication that, when used in conjunction with diet and exercise, has a proven track record in overweight and obese individuals. The most common adverse effects are abnormal skin sensations, dizziness, altered taste, insomnia, constipation, and dry mouth, more severe issues can occur.May 19, 2016 · Long-term users may also experience unwanted long-term side effects resulting from changes to physiology and neurobiology that accumulate over an extended period of time. Individual Factors Hypothetically, two individuals may commence Qsymia treatment on the same day, at the same dose, and avoid using co-administered substances. Extreme happiness or sadness. Symptoms of dangerously high blood pressure, such as severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, or seizures. These symptoms can indicate a serious phentermine side effect.Taking this medication late in the day may cause trouble sleeping ( insomnia ). Swallow the capsules whole. Do not crush or chew the capsules. Doing so can release all of the drug at once,...diarrhea. dry mouth and tongue. bad taste in your mouth. constipation*. headaches*. mild allergic reaction *†. * To learn more about this side effect, see the “Side effects explained ...Nov 2, 2022 · Phentermine (Adipex-P, Lomaira) is a prescription medicine used to lessen appetite. It can help weight loss by making you less hungry. Or it can help you feel full longer. Phentermine also is offered combined with topiramate for weight loss (Qsymia). The combined drug is approved for long-term use. Symptoms of severe phentermine side effects include ( 3 , 4 ): Chest pain. Pounding or irregular heartbeat, or fluttering in your chest. Lightheadedness or faintness. Shortness of breath, even with only mild exertion. Swelling in your legs, ankles, or feet (edema) Slurred speech or weakness on one side of your body.Phentermine and Qsymia are both medications used for weight loss. Phentermine is only approved for short-term usage, while Qsymia is approved for long-term use. Topiramate is a medication used to treat seizures and prevent migraines. It also happens to have a noticeable weight loss effect, although it’s not approved in Canada solely for ...After stopping phentermine, some people experience feelings of weariness and fatigue due to the sudden lack of chemical stimulation. If you are tired after stopping phentermine, take care to: Get enough sleep. Fuel your body with healthy foods: avoid high-fat, high-carb, and high-sugar goods that may worsen fatigue. Stay lightly active.Sep 21, 2018 · Using nonexposed periods in former users as a comparison achieves partial balance for obesity status. Second, because the signal of potential concern with Qsymia is increased heart rate—an effect that does not persist after the drug is withdrawn—the potential for carryover effects beyond current use was considered remote. Key variables Apr 30, 2014 · This review showed that combining low doses of phentermine and topiramate for the treatment of obesity minimized side effects while maintained weight loss efficacy. The side effects were paraesthesia, taste changes and dry mouth. Weight loss induced by the combination was associated with improved BP through one and two years of treatment. This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen. If you are taking any of these drugs: Linezolid or methylene blue. If you are pregnant or may be pregnant. Do not take this drug if you are pregnant. If you are breast-feeding.Mar 22, 2019 · An inexpensive weight-loss drug approved 60 years ago for only short-term use also may be safe and effective for longer-term treatment, according to a study conducted by researchers at Wake Forest ... These are the most common Topamax side effects, according to the manufacturer: Loss of appetite, changes in taste, weight loss, stomach pain, and even anorexia. GI side effects (nausea, diarrhea, indigestion) Tiredness. Paresthesia (tingling or prickling sensations) Speech problems. Cognitive dysfunction (trouble with memory and thinking) Upper ...Dec. 4, 2019 — A new study finds the only reliable way to measure exposure to radon gas is with a long-term testing kit, 90 or more days. Researchers placed two test kits, a short term (five-day ...This combination consists of fixed lower doses of phentermine and topiramate (3.75/23, 7/46, 11.25/69 and 15/92 mg) and is available in capsules under the brand name Qsymia. Common side effects of phentermine include nervousness, excitability, insomnia, headache, dry mouth, sweating, tachycardia, palpitations, nausea, constipation, and thirst.
The latest weight loss drugs work in a new way to help you shed pounds with minimal side effects. Learn how they do it and why you take them long term. ... (Qsymia®): This medication also .... Joseph d
Mar 13, 2023 · weight loss. impaired taste (changes in how things taste) trouble with memory. More common side effects in people taking Topamax for epilepsy include: tingling in the legs and arms. loss of ... Oct 26, 2022 · Common Qsymia side effects may include: joint pain, ankle sprain; flu-like symptoms; dizziness; constipation; numbness or tingly feeling; sleep problems (insomnia); dry mouth, changes in your sense of taste; or. mood changes, feelings of low self-worth, loss of interest in things you once enjoyed, ... Studies show that on average, people taking Topamax lose around 11 lbs. Higher doses and longer duration of use generally result in more weight loss. The most common side effects associated with Topamax for weight loss are abnormal skin sensations (like burning, tingling, numbness), altered sense of taste, and slowed thinking and movements.Apr 21, 2022 · Topamax withdrawal can occur when it’s stopped abruptly instead of tapered. The greatest risk is that your seizures worsen. Instead of stopping Topamax at once, your HCP can help you taper your dosage gradually. 7. Gabapentin (Neurontin) Gabapentin (Neurontin) is FDA-approved to treat seizures and nerve pain. Phentermine-Topiramate Capsule, Extended Release Multiphase 24 Hr (Capsule, ER Hr) - Uses, Side Effects, and More Common Brand(S): Qsymia Generic Name(S): phentermine-topiramate Jun 4, 2020 · This combination consists of fixed lower doses of phentermine and topiramate (3.75/23, 7/46, 11.25/69 and 15/92 mg) and is available in capsules under the brand name Qsymia. Common side effects of phentermine include nervousness, excitability, insomnia, headache, dry mouth, sweating, tachycardia, palpitations, nausea, constipation, and thirst. Apr 30, 2014 · This review showed that combining low doses of phentermine and topiramate for the treatment of obesity minimized side effects while maintained weight loss efficacy. The side effects were paraesthesia, taste changes and dry mouth. Weight loss induced by the combination was associated with improved BP through one and two years of treatment. The SELECT trial is the long-term cardiovascular outcomes trial for Wegovy that aims to assess its effects on heart disease and stroke in patients with overweight and obesity; it is currently ongoing and expected to be completed in September 2023. Anti-obesity medication management: An evolving landscapeExtreme happiness or sadness. Symptoms of dangerously high blood pressure, such as severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, or seizures. These symptoms can indicate a serious phentermine side effect.Mar 29, 2022 · Tardive dyskinesia is a movement disorder that is a side effect of medications, especially first-generation antipsychotics. Less common causes are second-generation antipsychotics, antidepressants, mood stabilizers, antiepileptic drugs, movement disorder medications, antiemetics, and decongestants. Two medications have been approved to treat ... It is also commonly prescribed to prevent migraines. Mild topiramate side effects include a “pins and needles” feeling, weight loss, and dizziness. Trouble focusing or thinking are also possible, especially when taking higher doses. High body temperature, suicidal thoughts, and eye problems are rare topiramate side effects.Qsymia's results have been clinically tested in two long-term studies with ... QSYMIA CAN CAUSE SERIOUS SIDE EFFECTS, INCLUDING: Birth defects (cleft lip/cleft palate). If you take Qsymia during ... Ozempic, a medication used in type 2 diabetes, is currently under review by the FDA to be approved for weight loss in overweight or obese adults. Phentermine may be a more accessible option to help you lose weight, but it should only be used for a few weeks. Both Ozempic and phentermine can help to curb your appetite so that you eat fewer ...It is also commonly prescribed to prevent migraines. Mild topiramate side effects include a “pins and needles” feeling, weight loss, and dizziness. Trouble focusing or thinking are also possible, especially when taking higher doses. High body temperature, suicidal thoughts, and eye problems are rare topiramate side effects.Common Side Effects of Weight Loss Drugs. Increased blood pressure and heart rate, insomnia, nervousness, restlessness, dependence, abuse or withdrawal may occur with long-term use. When given as a single agent, phentermine is not implicated in valvular heart disease; avoid use at bedtime..
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